Anupco


ANCOMOX 50

Water soluble powder

COMPOSITION

Amoxicillin trihydrateá eq. 500 mg Amoxicilliná- Excipents up to 1 g

PHARMACOLOGICAL PROPERTIES

Amoxcillin is a semi-synthetic, acid-stable broadspectrum penicillin. It inhibits peptidoglycan synthesis of the bacterial cell wall and has a fast bacteriocidal action. Amoxicillin is active against a number of Gram-positive and Gram-negative bacteria. Resistance against aminopenicillins most often is by plasmid-mediated production of penicillinase and occurs most frequently in enterobacteriaceae (E. coli, Salmonella spp.) and Staphylococci.

The absorption from the gastrointestinal tract is little influenced by the presence of food (bioavailability appr. 60% in chickens). Amoxcillin is about 30% bound to serum proteins. The concentrations in liver, bile, kidneys, urine, intestinalátissues and contentsáare clearly higher than in the blood.áHere, therapeutic active concentrationsácan even be obtained against less susceptibleágerms (e.g. against enteropathogenic bacteria of the gastrointestinal tract). Although the concentrations in the respiratory tract are usually lower than in the blood, they usually exceed the MIC-values of most respiratory pathogens. Amoxicillin is partly metabolised and is mainly excreted with urine, to a lesser extent with the bile. The non-absorbed fraction is excreted with the faeces.

INDICATIONS

For the treatment of infections caused by amoxicillin sensitive germs in poultry, pigs and calves.

CONTRA-INDICATIONS

Do not use in animals with a known hypersensitivity towards penicillins and cephalosporins.

Do not use in ruminating animals. Do certainly not use in rodents.

DOSAGE AND MODE OF ADMINISTRATION

Calves (non-ruminating): 21 mg ANCOMOX 50 per kg b.w. per day during 4-5 days

Pigs: 10-20 mg ANCOMOX 50 per kg b.w. per day during 4-5 days.

Poultry: 28 mg ANCOMOX 50 per kg b.w. per day during 5 days.

To be administered orally with the food or water.

Prevention Treatment
Poultry 100g in 500 litres of drinking water for 5 days 100g in 200 litres of drinking water for 5 days
Pigs 100g in 600 litres of drinking water for 4-5 days 100g in 400 litres of drinking water for 4-5 days
Calves (non-ruminating) - 1g per 50 kg b.w. 2x/day for 4-5 days

UNDESIRABLE EFFECTS

Allergic reactions seldom may occur.

Gastrointestinal side effects (diarrhoea) possibly may occur.

SPECIAL PRECAUTIONS FOR USE AND WARNINGS

Contact dermatitis may occur in hypersensitive persons. Direct contact with the powder should be avoided. Periodic control of in vitro antibiotic sensitivity of field isolates is advisable. Drinking water facilities (tanks, conduite pipes, nipples, etc.) should be cleaned properly after cessation of medication.

PACK SIZE

100 g, 1 kg.

Please be aware that product specifications and availability can differ between countries. For detailed information in this regard, please contact us.

You are viewing the English version of this website enesfr