Anupco


ANFLOX GOLD

Oral solution

COMPOSITION

Norfloxacin USP 200 mg/ml

PHARMACOLOGICAL PROPERTIES

Norfloxacin has potent antimicrobial activities against many pathogens, including E. coli, Staphylococcus spp., Pseudomonas aeruginosa and Mycoplasma gallisepticum. Norfloxacin is well absorbed orally. Peak serum concentrations are reached 20 minutes post-dosing, with an elimination t 1/2 of 12 hours and a bioavailability of 57%. Norfloxacin tends to penetrate the tissues rather slowly, with peak concentrations appearing 8 hours after dosing for all tissues except fat, where peak concentrations are reached at 24 hours after the oral dose. Norfloxacin is metabolized by the liver and excreted primarily in the urine. The elimination t 1/2 for a single IV dose is approximately 8 hours.

INDICATIONS

Turkeys, broilers, broiler breeders and replacement chickens: ANFLOX GOLD is indicated for diseases of the respiratory and alimentary tract that are of bacterial and mycoplasmal origin, e.g. pasteurellosis, coli-bacilliosis, coli-septicaemia and salmonellosis.

Crustaceans: ANFLOX GOLD is indicated for the treatmentáof infections caused by vibrio, i.e. V. parahaemolyticus, V. alginolyticus, V. anguillarum, V. herveyi, also Pseudomonas spp., Aeromonas spp.,áandámycoplasmas.

Where possible, use sensitivity testing to confirm ANFLOX GOLD as product of choice.

CONTRA-INDICATIONS

áHypersensitivity to norfloxacin and other quinolone group antibiotics is contra-indicated.

DOSAGE AND MODE OF ADMINISTRATION

Poultry:

Anflox Gold is administered via the drinking water. Medicated water shouldábe made up immediately prior to provision. Medicated water should be supplied continuously throughout the treatment period and no other water should be made available. The dosage rate is 12 mg norfloxacin per kg b.w. for 3-5 days: under normal circumstances this equates to a dose of 25 ml ANFLOX GOLDáper 100 litres of drinking water.

Crustaceans:

Administer via the feed. The dosage rate is 12 mg norfloxacin per kg biomass; this equates to 1-1.5 litres of ANFLOX GOLDáper 1000 kg of feed.

UNDESIRABLE EFFECTS

Arthropathies are reported in laboratory animals following norfloxacin treatment. In poultry these effects have not been seen, probably because doses were not high enough to induce an arthropathy.

SPECIAL PRECAUTIONS AND WARNINGS

Avoid usingáwith other medications. ANFLOX GOLD may be mixed and used at the same time as water soluble live virus vaccines, or anticoccidials which are administered in the drinking water.

PACK SIZE

500 ml and 1000 ml

Please be aware that product specifications and availability can differ between countries. For detailed information in this regard, please contact us.

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