Anupco


ANIZOLE 25

Oral Suspension

COMPOSITION

Albendazole 25 mg/ml.

PHARMACOLOGICAL PROPERTIES

A total spectrum multi-purpose anthelmintic for control of the following types of internal parasites in sheep, goats and cattle:

Gastro-intestinal roundworms: Bunostomum, Chabertia, Cooperia, Haemonchus, Nematodirus, Oesophagostomum, Ostertagia, Strongyloides and Trichostrongylus spp.

Lungworms: Dictyocaulus viviparus and D. filaria.

Tapeworms: Monieszia expansa.

Adult liver-flukes: Fasciola hepatica.

In ruminants albendazole suspension is slowly and almost completely absorbed from the rumen, whereupon it is rapidly metabolised by the first pass in the liver mainly to albendazole sulphoxide subsequent to albendazole sulphone and other metabolites. In ruminants it is predominantly excreted in the urine. Billiary elimination accounts for about 15% in sheep. Most of the excreted metabolites are unconjugated.

INDICATIONS

ANIZOLE 25 is indicated in the treatment of mature and immature roundworms and lungworms, including inhibited Type II Ostertagiasis in cattle, and flukes. It also removes both heads and segments of roundworms.

CONTRA-INDICATIONS

Do not exceed the recommended dose in females during early pregnancy.

DOSAGE AND MODE OF ADMINISTRATION

ANIZOLE 25 is a pale green free flowing suspension for administration as an oral drench, suitable for use with most types of automatic drenching equipment.

Sheep:

Worm dose: Approximately 5 mg albendazole per kg bodyweight. Up to 15kg: 2.5 ml/ 10 kg bodyweight. Above 15 kg: 2 ml/ 10 kg bodyweight.

Example:áááá Weightááááááááááááá Dose

áááááááááááááááááááááá 10kgááááááááááááááááá 2.5 ml

áááááááááááááááááááááá 20kgáááááááááááááááá 4.0 ml

Fluke and worm dose: Approximately 7.5 mg albendazole per kg bodyweight. Equivalent to 3 ml per 10 kg bodyweight.

Example:ááááá Weightááááááááááá Dose

ááááááááááááááááááááááá 20 kgááááááááááááááá 6 ml

ááááááááááááááááááááááá 50 kgáááááááááááááááá 15 ml

Cattle:

Worm Dose: Approximately 7.5 mg albendazole per kg bodyweight. Equivalent to 15 ml per 50 kg bodyweight.

ExampleááááááááWeightááááááááááááá Dose

ááááááááááááááááááááááá 100 kgáááááááááááááá 30 ml

áááááááááááááááááááááá 300 kgáááááááááááááá 90 ml

Fluke and worm dose: Approximately 10 mg albendazole per kg bodyweight. Equivalent to 20 ml per 50 kg bodyweight.

Example:ááááááá Weightááááááááááááá Dose

ááááááááááááááááááááááááá 100 kgáááááááááááááá 40 ml

áááááááááááááááááááááááá 300 kgáááááááááááááá120 ml

UNDESIRABLE EFFECTS

By research and experiences in the field it was shown that albendazole is a very safe drug. No side effects are likely to be expected at recommended doses.

SPECIAL PRECAUTIONS AND WARNINGS

Anizole 25 is not recommended for the treatment of acute fascioliasis in sheep. During tupping do not dose ewes at the fluke and worm dose rate, or for 1 month after removing rams.

With cattle, do not exceed the fluke and worm dose during the first month of pregnancy.

Cattle suffering from severe lung damage due to heavy lungworm infection may continue to cough for some weeks after the treatment.

PACK SIZE

1000 ml and 2500ml.

Please be aware that product specifications and availability can differ between countries. For detailed information in this regard, please contact us.

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