Anupco


FLUMEX 20

Oral solution

COMPOSITION

Flumequine 200 mg/ ml

PHARMACOLOGICAL PROPERTIES

Flumequine is a synthetic 4-quinolone antibacterial agent of the 2nd generation. It interferes with bacterial DNA synthesis by inhibiting the α- subunits of DNA-gyrase, that controls the topological state of DNA, which results in a rapid bactericidal action. The spectrum of flumequine comprises among others Gram-negative bacteria e.g. Escherichia coli. Most Gram-positive bacteria and obligate anaerobes are inherently resistant. Flumequine is rapidly and well absorbed after its oral administration to chickens. Serum protein binding is about 30%. Flumequine is widely distributed throughout the body and can be detected in most organs and tissues, including the brain. Concentrations higher than or equal to plasma concentrations are attained in e.g. kidneys, liver, muscles, heart, lungs, cartilage and content of the gastro-intestinal tract. Flumequine is extensively metabolised in most animal species and rapidly excreted with faeces and urine.

INDICATIONS

FLUMEX 20 is indicated in the prevention and treatment of infectious diseases caused by Gram-negative bacteria: collibacillosis, salmonellosis, fowl cholera, staphylococci infections, pasteurellosis and others.

CONTRA-INDICATIONS

Not for use in laying hens.

DOSAGE AND MODE OF ADMINISTRATION

12ámg flumequine per kg bodyweight, equivalent to 50ml FLUMEX 20 per 100 litre drinking water for 3-5 days.

UNDESIRABLE EFFECTS

No adverse effects known if used at therapeutic doses.

SPECIAL PRECAUTIONS AND WARNINGS

It is advised to reserve this product for treatment of affections which did not previously respond adequately, or are known to be unresponsive, to other classes of antibiotics.

This product should only be used on the basis of an antibiogram.

Pack Size:

1000 ml bottles.

Please be aware that product specifications and availability can differ between countries. For detailed information in this regard, please contact us.

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